Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.54 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757724 | 0.94 | GPR139 (0.62) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11380224 | 0.86 | POLB (0.64) | ALDH1A1HPGDCYP1A2CYP2C19ERCC5 | |
| SCHEMBL8001466 | 0.85 | ALDH1A1 (0.67) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12245344 | 0.85 | CDK1 (0.63) | HPGDTP53P2RX7CA1CA2 | |
| SCHEMBL16252980 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL343657 | 0.85 | MEN1 (0.49) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29195047 | 0.85 | P2RX7 (0.55) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20694515 | 0.83 | HPGD (0.62) | ALDH1A1HPGDCYP1A2P2RX7CA1 | |
| SCHEMBL9048413 | 0.83 | FADS1 (0.54) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12901004 | 0.83 | EGLN1 (0.55) | HPGDGPR139P2RX7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794520-B | Synthesis method of boric acid citrate compounds including Eszolomide | 北京大学 | 2020-07-24 | — | — | CN | claimed |
| CN-108794520-A | The synthetic method of boric acid citric acid ester type compound including Ai Shazuo meter | 北京大学 | 2018-11-13 | — | — | CN | claimed |
| EP-3805237-B1 | SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND | JIANGSU CHUANGTE PHARMACEUTICAL TECH CO LTD (CN) | 2026-01-28 | — | — | EP | disclosed |
| US-20230265111-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-08-24 | — | — | US | disclosed |
| US-20230265111-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-08-24 | — | — | US | disclosed |
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20220009948-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-01-13 | — | — | US | disclosed |
| EP-3672978-B1 | PROCESS FOR MAKING IXAZOMIB AND ITS INTERMEDIATES | SYNTHON BV (NL) | 2021-10-06 | — | — | EP | disclosed |
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) | 2021-07-15 | — | — | US | disclosed |
| EP-2730580-A1 | Boronate ester compounds and pharmaceutical compositions thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-2730581-A1 | Boronate ester compounds and pharmaceutical compositions thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-05-14 | — | — | EP | disclosed |
| US-20140018301-A9 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20140018301-A9 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20130165390-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130165390-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-20090325903-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090325903-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| WO-2009154737-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018301-A9 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PSMB5, PSMB11, PSMB3 | ALDH1A1 3884/4885HPGD 3766/4885CYP1A2 2339/4885 |
| US-20090325903-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PSMB5, PSMB11, PSMB3 | ALDH1A1 3884/4885HPGD 3766/4885CYP1A2 2339/4885 |
| US-20210214377-A1 | SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF | SEM1, VIP, PSMB11 | ALDH1A1 4592/4885HPGD 2888/4885CYP1A2 4739/4885 |
| US-20230265111-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PSMB5, PSMB11, PSMB3 | ALDH1A1 3884/4885HPGD 3766/4885CYP1A2 2339/4885 |
| US-20220009948-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PSMB5, PSMB11, PSMB3 | ALDH1A1 3884/4885HPGD 3766/4885CYP1A2 2339/4885 |
| US-11542283-B2 | Synthesis of peptide borate ester compound and use thereof | SEM1, VIP, PSMB11 | ALDH1A1 4592/4885HPGD 2888/4885CYP1A2 4739/4885 |
| US-20130165390-A1 | BORONATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PSMB5, PSMB11, PSMB3 | ALDH1A1 3884/4885HPGD 3766/4885CYP1A2 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.