Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
| ▸ | GCK | P35557 | 2/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.46 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminohippuric Acid SCHEMBL9327154 | 0.83 | MAPT (0.64) | FADS1CCR2NOS2RECQLKDM4E | |
| SCHEMBL8002583 | 0.83 | ALDH1A1 (0.64) | ALDH1A1EGLN1FLT1GPR139CYP1A2 | |
| SCHEMBL12245344 | 0.82 | CDK1 (0.63) | MAPTEGLN1VEGFAFLT1HPGD | |
| SCHEMBL11689255 | 0.82 | NOS2 (0.63) | FADS1CCR2GCKNOS2RECQL | |
| SCHEMBL343657 | 0.82 | MEN1 (0.49) | ALDH1A1EGLN1VEGFAFLT1GPR139 | |
| SCHEMBL1095186 | 0.81 | ALDH1A1 (0.70) | FADS1GCKNOS2RECQLKDM4E | |
| SCHEMBL12900998 | 0.81 | EGLN1 (0.57) | RECQLALDH1A1EGLN1VEGFAFLT1 | |
| SCHEMBL15630978 | 0.81 | KEAP1 (0.59) | FADS1KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL10705234 | 0.81 | CDK1 (0.57) | FADS1GCKNOS2RECQLALDH1A1 | |
| SCHEMBL11380224 | 0.80 | POLB (0.64) | RECQLKDM4EMAPTHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |