Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.35 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1550135 | 0.85 | STAT6 (0.38) | STAT6DRD2BCAT1CYP51A1CCKBR | |
| SCHEMBL19856953 | 0.85 | STAT6 (0.38) | STAT6DRD2BCAT1CYP51A1CCKBR | |
| SCHEMBL7995048 | 0.79 | DRD2 (0.43) | STAT6DRD2CYP51A1CCKBRALDH1A1 | |
| SCHEMBL7989864 | 0.75 | PYGL (0.37) | DRD2BCAT1CYP51A1GHSRPYGL | |
| SCHEMBL8002404 | 0.75 | PYGL (0.37) | DRD2BCAT1CYP51A1ALDH1A1GHSR | |
| SCHEMBL8004923 | 0.74 | PYGL (0.37) | DRD2BCAT1CYP51A1PYGL | |
| SCHEMBL7998609 | 0.73 | DRD2 (0.47) | STAT6DRD2CYP51A1CCKBRALDH1A1 | |
| SCHEMBL7989861 | 0.73 | DRD2 (0.47) | STAT6DRD2CYP51A1CCKBRALDH1A1 | |
| SCHEMBL8002402 | 0.73 | STAT6 (0.37) | STAT6BCAT1CYP51A1CCKBRALDH1A1 | |
| SCHEMBL7996254 | 0.73 | STAT6 (0.37) | STAT6CYP51A1CCKBRLMNAGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146182-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-03 | — | — | WO | disclosed |