Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481801 | 0.88 | KMT2A (0.38) | P2RX7KMT2AARLMNATHRA | |
| SCHEMBL8002833 | 0.86 | P2RX7 (0.39) | P2RX7KMT2AARLMNATHRA | |
| SCHEMBL7480013 | 0.85 | P2RX7 (0.41) | P2RX7KMT2AARTHRATHRB | |
| SCHEMBL7480005 | 0.83 | P2RX7 (0.39) | P2RX7KMT2AARTHRATHRB | |
| SCHEMBL7477804 | 0.77 | THRB (0.47) | P2RX7KMT2ATHRATHRB | |
| SCHEMBL7480097 | 0.76 | NPBWR1 (0.34) | P2RX7KMT2AARTHRATHRB | |
| SCHEMBL8347711 | 0.72 | THRB (0.52) | P2RX7KMT2ATHRATHRB | |
| SCHEMBL7472949 | 0.70 | MEN1 (0.51) | P2RX7KMT2ATHRATHRB | |
| SCHEMBL7838560 | 0.70 | KMT2A (0.56) | KMT2ALMNATSHRALDH1A1MAPT | |
| SCHEMBL7839566 | 0.69 | KMT2A (0.39) | KMT2AARLMNATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831088-B1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5985875-A | USEFUL AS ANTI-PROTOZOAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0831088-A1 | 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-25 | — | — | EP | disclosed |