Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164728 | 0.77 | SIRT2 (0.42) | ALDH1A1MEN1LMNAKMT2AATM | |
| SCHEMBL7247143 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MTNR1ACA1CA2CYP2C19 | |
| SCHEMBL7163976 | 0.70 | MTNR1A (0.43) | ALDH1A1LMNAMTNR1AMTNR1BCA1 | |
| SCHEMBL7164487 | 0.68 | SIRT2 (0.38) | ALDH1A1LMNAKMT2AKDM4EGAA | |
| SCHEMBL487112 | 0.63 | TRPV1 (0.44) | ALDH1A1MEN1KMT2AMTNR1ACA1 | |
| SCHEMBL6437908 | 0.60 | TRPV1 (0.55) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6827222 | 0.59 | TRPV1 (0.59) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL6825142 | 0.59 | KDM4E (0.72) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8755775 | 0.59 | CASP6 (0.48) | ALDH1A1MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL8923098 | 0.58 | PLAU (0.54) | ALDH1A1MEN1LMNAKMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000025789-A1 | A METHOD OF TREATING ENDOMETRIOSIS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |