Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8862871 | 0.96 | HSP90AB1 (0.40) | HSP90AB1LTB4RIGFBP3MPOALDH1A1 | |
| SCHEMBL8862784 | 0.82 | IGFBP3 (0.39) | HSP90AB1LTB4RIGFBP3ALDH1A1HSD17B10 | |
| SCHEMBL8862704 | 0.80 | LTB4R (0.46) | HSP90AB1LTB4RIGFBP3MPOALDH1A1 | |
| SCHEMBL27379780 | 0.80 | SLC2A1 (0.47) | HSP90AB1LTB4RMPOALDH1A1HSD17B10 | |
| SCHEMBL7797896 | 0.79 | HSP90AB1 (0.51) | HSP90AB1LTB4RALDH1A1HSD17B10SLC2A1 | |
| SCHEMBL27355398 | 0.76 | ALDH1A1 (0.43) | LTB4RALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL9094776 | 0.76 | LTB4R (0.41) | HSP90AB1LTB4RIGFBP3ALDH1A1HSD17B10 | |
| SCHEMBL29801535 | 0.74 | LTB4R (0.43) | HSP90AB1LTB4RSLC2A1 | |
| SCHEMBL7796197 | 0.73 | PDE4A (0.44) | HSP90AB1LTB4RSLC5A2 | |
| SCHEMBL7794741 | 0.73 | CHRM4 (0.42) | HSP90AB1LTB4RIGFBP3ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046206-A | Method of treating a patient having a precancerous lesions with amide quinazoline derivatives | CELL PATHWAYS, INC. (US) | 2000-04-04 | — | — | US | disclosed |