Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313700 | 1.00 | CTSB (0.32) | CTSBPPP3CBCTSS | |
| SCHEMBL8005334 | 0.94 | CTSB (0.32) | CTSBPPP3CB | |
| SCHEMBL12356928 | 0.94 | CTSB (0.32) | CTSBPPP3CB | |
| SCHEMBL12369706 | 0.92 | CTSS (0.32) | CTSBPPP3CBCTSS | |
| SCHEMBL10247430 | 0.92 | — | — | |
| SCHEMBL15216171 | 0.90 | CTSB (0.35) | CTSBPPP3CBCTSS | |
| SCHEMBL15026861 | 0.90 | CTSB (0.34) | CTSBPPP3CBCTSS | |
| SCHEMBL7994784 | 0.89 | UCHL1 (0.36) | CTSBPPP3CBCTSS | |
| SCHEMBL312962 | 0.89 | UCHL1 (0.36) | CTSBPPP3CBCTSS | |
| SCHEMBL312963 | 0.89 | UCHL1 (0.36) | CTSBPPP3CBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099596-A2 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARAMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |