SCHEMBL27360248

SCHEMBL27360248

Clc1ccc2c(c1)CCc1c-2ccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 3/20 0.44
SRD5A2 P31213 2/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
ACHE P22303 2/20 0.43
HTT P42858 1/20 0.42
CYP2A6 P11509 1/20 0.41
HSP90AA1 P07900 1/20 0.39
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
GLA P06280 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP19A1 P11511 6/20 0.37
CYP11B1 P15538 6/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27324434 0.88 TDP2 (0.38) SRD5A1SRD5A2KDM4ECYP1A2GLA
SCHEMBL6705946 0.81 BCHE (0.45) SRD5A1SRD5A2ACHEHTTCYP2A6
SCHEMBL15282381 0.76 SRD5A1 (0.64) SRD5A1SRD5A2HTTHSP90AA1CYP19A1
SCHEMBL4068688 0.75 SRD5A1 (0.55) SRD5A1SRD5A2HTTHSP90AA1CYP19A1
SCHEMBL19152708 0.72 CA1 (0.48) CA1CA2CA4CA6ACHE
SCHEMBL8005649 0.71 ACHE (0.78) ACHEKDM4E
SCHEMBL29481017 0.70 ALDH1A1 (0.50) ACHEHTTCYP2A6KDM4ECYP1A2
SCHEMBL54652 0.70 ALDH1A1 (0.50) ACHEHTTCYP2A6KDM4ECYP1A2
SCHEMBL3369697 0.69 HTT (0.55) SRD5A1SRD5A2HTTCYP19A1CYP11B1
SCHEMBL14267931 0.69 TRPM4 (0.41) CA1CA2CA4CA6ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1069729-A Dihydropyridazinone, pyridazinone and related compound thereof as sterilant ROHM & HAAS (US) 1993-03-10 CN disclosed