Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 4/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGAV | P06756 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767143 | 0.81 | LMNA (0.47) | CASRLMNA | |
| SCHEMBL444179 | 0.81 | CASR (0.74) | CASRP2RX7CCR3LMNAKMT2A | |
| SCHEMBL8005868 | 0.77 | POLB (0.60) | CASRCCR3LMNAKMT2AMEN1 | |
| SCHEMBL8007408 | 0.75 | CASR (0.64) | CASRP2RX7LMNAKMT2AKCNQ2 | |
| SCHEMBL14401688 | 0.75 | ALDH1A1 (0.60) | ITGB3ITGAVITGB1ITGA5LMNA | |
| SCHEMBL14271765 | 0.74 | MAPK1 (0.50) | LMNAKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7995663 | 0.74 | CASR (0.62) | CASRP2RX7LMNAKMT2AKCNQ2 | |
| SCHEMBL8532166 | 0.73 | CCR3 (0.56) | CASRITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL7305489 | 0.72 | HPGD (0.72) | LMNAKMT2AMEN1MAPT | |
| SCHEMBL8007374 | 0.72 | CASR (0.60) | CASRP2RX7KMT2AMEN1KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |