Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 10/20 | 0.47 |
| ▸ | KCNK10 | P57789 | 8/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919991 | 0.83 | LMNA (0.53) | TRPV1ALDH1A1KDM4ETDP1KCNK2 | |
| SCHEMBL10743419 | 0.81 | ALDH1A1 (0.35) | TRPV1ALDH1A1KDM4ETDP1KCNK2 | |
| SCHEMBL1015553 | 0.81 | KCNK2 (0.57) | TRPV1ALDH1A1KDM4ETDP1KCNK2 | |
| SCHEMBL10740573 | 0.81 | ALDH1A1 (0.50) | TRPV1ALDH1A1KDM4ETDP1KCNK2 | |
| SCHEMBL2541283 | 0.79 | KIF11 (0.54) | TRPV1ALDH1A1KDM4ETDP1KCNK2 | |
| SCHEMBL1160810 | 0.79 | HPGD (0.59) | TRPV1ALDH1A1KDM4ETDP1KCNK2 | |
| SCHEMBL11451464 | 0.79 | ALDH1A1 (0.44) | TRPV1ALDH1A1KDM4EEPHX2NR1H4 | |
| SCHEMBL8005997 | 0.79 | KCNK2 (0.54) | TRPV1ALDH1A1KDM4ETDP1KCNK2 | |
| SCHEMBL1448525 | 0.77 | TSHR (0.49) | TRPV1ALDH1A1KCNK2KCNK10NPC1 | |
| SCHEMBL11106674 | 0.76 | KCNK2 (0.51) | TRPV1ALDH1A1KDM4ETDP1KCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12209094-B2 | CCR2 receptor antagonists and uses thereof | CENTREXION THERAPEUTICS CORPORATION (US) | 2025-01-28 | — | — | US | disclosed |
| US-20240109909-A1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | ANKURA TRUST COMPANY, LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT | 2024-04-04 | — | — | US | disclosed |
| US-11773066-B2 | Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230278955-A1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | UNIV KYOTO (JP) | 2023-09-07 | — | — | US | disclosed |
| US-11731981-B2 | CCR2 receptor antagonists and uses thereof | CENTREXION THERAPEUTICS CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| US-20220017473-A1 | INDAZOLYLCYANOETHYLAMINO COMPOUND, COMPOSITIONS OF SAME, METHOD OF MAKING, AND METHODS OF USING THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2022-01-20 | — | — | US | disclosed |
| US-20220002310-A1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | ANKURA TRUST COMPANY, LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT | 2022-01-06 | — | — | US | disclosed |
| EP-3883648-A1 | INDAZOLYLCYANOETHYLAMINO COMPOUND, COMPOSITIONS OF SAME, METHOD OF MAKING, AND METHODS OF USING THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| CN-113260419-A | Indazolyl cyanoethylamino compounds, compositions thereof, methods of making the same, and methods of using the same | 勃林格殷格翰动物保健美国公司 | 2021-08-13 | — | — | CN | disclosed |
| WO-2021149818-A1 | COMBINATION AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER | 国立大学法人東京農工大学 | 2021-07-29 | — | — | WO | disclosed |
| US-4122281-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4113872-A | DIURETICS, SALURETICS, ANTIHYPERTENSIVE, ANTITHROMBOTIC AGENTS | BAKER AKTIENGESELLSHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4112109-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |
| US-4099011-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |
| US-4096152-A | DIURETICS, SALURETICS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-4069334-A | DIURETICS, HYPOTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
| US-4002641-A | DIURETICS, SALURETICS, HYPOTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731981-B2 | CCR2 receptor antagonists and uses thereof | CCR2, CCRL2, CCR1 | TRPV1 212/4885ALDH1A1 1767/4885KDM4E 4483/4885 |
| US-20230278955-A1 | VITAMIN D3 DERIVATIVES AND PHARMACEUTICAL USE THEREOF | VDR, CYP24A1, CYP2R1 | TRPV1 2094/4885ALDH1A1 256/4885KDM4E 1757/4885 |
| US-11773066-B2 | Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof | ACHE, DDT, NOTUM | TRPV1 2283/4885ALDH1A1 333/4885KDM4E 275/4885 |
| US-20220017473-A1 | INDAZOLYLCYANOETHYLAMINO COMPOUND, COMPOSITIONS OF SAME, METHOD OF MAKING, AND METHODS OF USING THEREOF | ACHE, DDT, NOTUM | TRPV1 2283/4885ALDH1A1 333/4885KDM4E 275/4885 |
| US-20240109909-A1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | CCR2, CCRL2, CCR1 | TRPV1 212/4885ALDH1A1 1767/4885KDM4E 4483/4885 |
| US-20220002310-A1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | CCR2, CCRL2, CCR1 | TRPV1 212/4885ALDH1A1 1767/4885KDM4E 4483/4885 |
| US-12209094-B2 | CCR2 receptor antagonists and uses thereof | CCR2, CCRL2, CCR1 | TRPV1 212/4885ALDH1A1 1767/4885KDM4E 4483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.