Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038279 | 0.86 | NISCH (0.36) | NISCHHTR2CNPC1 | |
| SCHEMBL31225112 | 0.80 | OPRM1 (0.32) | NISCH | |
| SCHEMBL7163648 | 0.76 | NISCH (0.39) | NISCHPARP10PARP11HTR2CNPC1 | |
| SCHEMBL9585140 | 0.74 | HTR2C (0.51) | PARP10PARP11IDO1HTR2C | |
| SCHEMBL14904833 | 0.71 | ADRA2A (0.54) | NISCHFYNCLK4DYRK1BHTR7 | |
| SCHEMBL15804315 | 0.70 | HTR7 (0.48) | NISCHPARP10PARP11HTR7CHRNB4 | |
| Hydrochloric Acid SCHEMBL9310385 | 0.70 | ADRA2A (0.53) | NISCHFYNCLK4DYRK1BHTR7 | |
| SCHEMBL31471473 | 0.70 | ACHE (0.69) | NISCHACHEIDO1METAP2CHRNB4 | |
| SCHEMBL29373699 | 0.70 | ACHE (0.69) | NISCHACHEIDO1METAP2CHRNB4 | |
| SCHEMBL301247 | 0.70 | ACHE (0.69) | NISCHACHEIDO1METAP2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130180-A | Catalyst for the polymerization of alpha-olefins containing substituted amino silane compounds | MONTELL NORTH AMERICA INC. (US) | 2000-10-10 | — | — | US | disclosed |