SCHEMBL8007196

SCHEMBL8007196

CSc1cccc(-c2nnn[nH]2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.46
ALOX5 P09917 1/20 0.40
DCUN1D1 Q96GG9 2/20 0.33
LRRK2 Q5S007 1/20 0.33
SYK P43405 1/20 0.33
ABCC1 P33527 2/20 0.33
ABCG2 Q9UNQ0 2/20 0.33
TGFBR1 P36897 1/20 0.33
NOTUM Q6P988 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
CHRM1 P11229 1/20 0.33
ABCB1 P08183 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
TP53 P04637 2/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12761250 0.82 GP6 (0.37) IDO1DCUN1D1TP53MAPTLMNA
SCHEMBL9700407 0.79 IDO1 (0.41) IDO1ALOX5TGFBR1NOTUMAKR1C3
SCHEMBL7157504 0.79 NISCH (0.40) ALOX5DCUN1D1LMNAPOLBMAPK1
SCHEMBL513232 0.77 ALDH1A1 (0.44) IDO1NOTUMTP53MEN1POLB
SCHEMBL4655029 0.75 GP6 (0.49) MAPTMEN1KMT2A
SCHEMBL13525158 0.75 ALDH1A1 (0.41) IDO1NOTUMTP53MEN1POLB
SCHEMBL27668175 0.74 CYP1A2 (0.33)
SCHEMBL11012914 0.74 KMT2A (0.33) TP53MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL704854 0.74 MGAM (0.43) IDO1NOTUMTP53MAPTLMNA
SCHEMBL1109610 0.74 ENPP2 (0.32) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143434-A HIGH LUMINANCE AND A HIGH LUMINESCENT EFFICIENCY AT A LOW DRIVING VOLTAGE AND HAS EXCELLENT STABILITY IN REPETITIONS OF USE FUJI PHOTO FILM CO., LTD. (JP) 2000-11-07 US disclosed
EP-0314104-B1 SILVER HALIDE PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1993-09-15 EP disclosed
US-5093222-A Contrast, negatives FUJI PHOTO FILM CO., LTD. (JP) 1992-03-03 US disclosed
EP-0314104-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0305545-A1 SUBSTITUTED ACRIDINE DERIVATIVES AND THEIR USE Hitachi Chemical Co., Ltd. (JP) 1989-03-08 EP disclosed
US-4740455-A Heat developable light-sensitive material containing polymethine FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed