SCHEMBL8007367

SCHEMBL8007367

COc1ccc(Oc2ccc(CO)cn2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HAO1 Q9UJM8 1/20 0.44
KDM4E B2RXH2 3/20 0.43
GAA P10253 1/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
BRCA1 P38398 1/20 0.42
HBB P68871 1/20 0.42
HSD17B10 Q99714 1/20 0.42
LTA4H P09960 2/20 0.42
LIPE Q05469 1/20 0.41
IL6 P05231 1/20 0.40
TLR7 Q9NYK1 1/20 0.40
P2RX3 P56373 1/20 0.40
IDO1 P14902 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29873318 0.87 KDM4E (0.58) RAB9ANPC1HTTKDM4EGAA
SCHEMBL23361553 0.87 KDM4E (0.58) RAB9ANPC1HTTKDM4EGAA
SCHEMBL28980410 0.85 APP (0.47) RAB9ANPC1HTTALDH1A1IDO1
SCHEMBL4597878 0.83 KDM4E (0.54) RAB9ANPC1KDM4EGAAALDH1A1
SCHEMBL20771833 0.83 MAOB (0.51) RAB9ANPC1HTTNPSR1RXFP1
SCHEMBL24570677 0.83 MEN1 (0.58) RAB9ANPC1HTTKDM4EALDH1A1
SCHEMBL8023066 0.83 RAB9A (0.44) RAB9ANPC1HTTNPSR1RXFP1
SCHEMBL8019976 0.83 P2RX3 (0.48) RAB9ANPC1HTTHAO1LTA4H
SCHEMBL510046 0.83 LTA4H (0.58) HTTALDH1A1LTA4HOPRM1OPRD1
SCHEMBL30879440 0.82 LMNA (0.62) RAB9ANPC1NPSR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346549-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2025-11-13 US disclosed
US-20250084023-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2025-03-13 US disclosed
US-20240140895-A1 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2024-05-02 US disclosed
WO-2009071504-A1 2,6-DISUBSTITUTED PYRIDINES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS SMITHKLINE BEECHAM CORPORATION (US) 2009-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084023-A2 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK RAB9A 2960/4885NPC1 4723/4885HTT 1216/4885
US-20250346549-A2 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK RAB9A 2960/4885NPC1 4723/4885HTT 1216/4885
US-20240140895-A1 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK RAB9A 2960/4885NPC1 4723/4885HTT 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.