Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816008 | 0.88 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19SMN1; SMN2NLRP3 | |
| SCHEMBL7257110 | 0.85 | MEN1 (0.72) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KCNMA1 | |
| SCHEMBL18473970 | 0.84 | NLRP3 (0.79) | CYP1A2CYP2C9CYP2C19SMN1; SMN2NLRP3 | |
| SCHEMBL7254155 | 0.84 | ALDH1A1 (0.54) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GAA | |
| SCHEMBL8006888 | 0.84 | HPGD (0.72) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KCNMA1 | |
| SCHEMBL6287677 | 0.81 | CYP1A2 (0.73) | CYP1A2CYP2C9CYP2C19SMN1; SMN2NLRP3 | |
| SCHEMBL7257115 | 0.81 | ALDH1A1 (0.64) | CYP1A2CYP2C9CYP2C19SMN1; SMN2NLRP3 | |
| SCHEMBL12407193 | 0.81 | SMN1; SMN2 (1.00) | CYP1A2CYP2C9CYP2C19SMN1; SMN2NLRP3 | |
| SCHEMBL10192134 | 0.80 | CYP1A2 (0.71) | CYP1A2CYP2C9CYP2C19SMN1; SMN2NLRP3 | |
| SCHEMBL6397287 | 0.80 | KCNMA1 (0.69) | SMN1; SMN2KCNMA1GAAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102827094-A | 2,3,6(8)-tri-substituted-3,4-dihydro-2H-1,3-benzoxazines compound | UNIV HUNAN SCI & TECHNOLOGY | 2012-12-19 | — | — | CN | disclosed |
| EP-0648816-B1 | Dyeing of leather with dyestuff mixtures | CIBA SC HOLDING AG (CH) | 2000-01-26 | — | — | EP | disclosed |
| EP-0648816-A1 | Dyeing of leather with dyestuff mixtures | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| US-5204453-A | Process for the preparation of 1:2 metal complex azo compounds by carrying out diazotization and coupling in the presence of a metal donor | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| US-5002586-A | Dyeing and printing of leather | SANDOZ LTD. (CH) | 1991-03-26 | — | — | US | disclosed |
| US-5001227-A | Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| US-4990598-A | Colorfastness | CIBA-GEIGY CORPORATION, A CORP. OF NEW YORK | 1991-02-05 | — | — | US | disclosed |
| US-4960870-A | DYEING WOOL, POLYAMIDES; FIBER REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4874848-A | FOR DYEING WOOL, LEATHER, POLYAMIDES BLACK OR BROWN | CIBA-GEIGY CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| US-4874849-A | FOR DYEING WOOL, POLYAMIDES, LEATHER ORANGE OR BROWN | CIBA-GEIGY CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| EP-0048693-A2 | Disazo dyestuffs, metal complexes thereof, their preparation and use | CIBA-GEIGY AG (CH) | 1982-03-31 | — | — | EP | disclosed |
| US-4318849-A | COPPER, NICKEL, CHROMIUM OR COBALT COMPLEXES OF AZO OR AZO-METHINE DYES | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |
| US-4256633-A | AZO DYES; AZOMETHINE DYES; WOOL, POLYAMIDES, AND LEATHER | CIBA-GEIGY CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4215042-A | PRINTING AND DYEING OF POLYAMIDES; COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |
| US-4116952-A | POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-RE29585-E | DYEING WOOL | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4033942-A | Chromium complex dye, including azo and azo methine dye compounds | CIBA-GEIGY AG (CH) | 1977-07-05 | — | — | US | disclosed |
| US-3978037-A | POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
| US-3933785-A | Azo compounds | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |