Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17983446 | 0.87 | ENPP3 (0.36) | METAP2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8250696 | 0.83 | METAP2 (0.44) | METAP2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL17066733 | 0.82 | ENPP3 (0.46) | METAP2MAPTMEN1KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28836149 | 0.82 | KMT2A (0.43) | METAP2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL12616942 | 0.81 | RAB9A (0.40) | MAPTALDH1A1HPGDTP53SMN1; SMN2 | |
| SCHEMBL24484639 | 0.80 | RAB9A (0.47) | METAP2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13545715 | 0.80 | PDGFRB (0.44) | METAP2MAPTALDH1A1HPGDTP53 | |
| SCHEMBL15823275 | 0.80 | RAD51 (0.43) | ALDH1A1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28574508 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3669956 | 0.80 | MEN1 (0.43) | MAPTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665468-B1 | Staining inhibitor for photopolymerizable compositions containing a tetrazole | MACDERMID IMAGING TECHNOLOGY (US) | 2000-04-19 | — | — | EP | disclosed |
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0131973-B1 | NEW AMIDINE DERIVATIVES OF 2-SUBSTITUTED 4-PHENILIMIDAZOLE | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-08-02 | — | — | EP | disclosed |
| US-4649150-A | ANTISECRETORY AGENTS | ISTITUTO DE ANGELI, S.P.A. (IT) | 1987-03-10 | — | — | US | disclosed |
| EP-0131973-A1 | New amidine derivatives of 2-substituted 4-phenilimidazole | ISTITUTO DE ANGELI S.p.A. (IT) | 1985-01-23 | — | — | EP | disclosed |