Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8250696 | 0.98 | METAP2 (0.44) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL17066733 | 0.96 | ENPP3 (0.46) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL17983446 | 0.89 | ENPP3 (0.36) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL13545715 | 0.82 | PDGFRB (0.44) | KDM4EALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL3669956 | 0.82 | MEN1 (0.43) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL24484639 | 0.82 | RAB9A (0.47) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL15823275 | 0.82 | RAD51 (0.43) | KDM4EALDH1A1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL8010306 | 0.82 | KEAP1 (0.41) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL28574508 | 0.82 | MAPT (0.47) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL1008901 | 0.81 | MEN1 (0.46) | KMT2AMEN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115023427-A | Pyrazolotriazines | 拜耳公司 | 2022-09-06 | — | — | CN | disclosed |