Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.71 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.71 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.71 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21430785 | 0.85 | EGFR (0.54) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| SCHEMBL13060204 | 0.84 | ALDH1A1 (0.74) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| SCHEMBL7903277 | 0.84 | KDM4E (0.62) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| SCHEMBL230147 | 0.84 | KDM4E (0.62) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| SCHEMBL230148 | 0.84 | KDM4E (0.62) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| SCHEMBL13164595 | 0.83 | MCL1 (0.68) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| Alpha-Cyano-4-Hydroxycinnamic Acid SCHEMBL26825 | 0.83 | KDM4E (1.00) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| SCHEMBL6344579 | 0.83 | MCL1 (0.68) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| SCHEMBL6344582 | 0.83 | MCL1 (0.68) | ALDH1A1KDM4ECYP3A4HPGDCISD1 | |
| Alpha-Cyano-4-Hydroxycinnamic Acid SCHEMBL26826 | 0.83 | KDM4E (1.00) | ALDH1A1KDM4ECYP3A4HPGDCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210855-A1 | USE OF MCT1 INHIBITORS TO ENHANCE INSULIN SENSITIVITY | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2023-07-06 | — | — | US | disclosed |
| US-9958449-B2 | Method for enzyme-mediated signal amplification | DAKO DENMARK A/S (DK) | 2018-05-01 | — | — | US | disclosed |
| US-20160274122-A1 | NEW METHOD FOR ENZYME-MEDIATED SIGNAL AMPLIFICATION | DAKO DENMARK APS (DK) | 2016-09-22 | — | — | US | disclosed |
| US-9366675-B2 | Method for enzyme-mediated signal amplification | DAKO DENMARK A/S (DK) | 2016-06-14 | — | — | US | disclosed |
| WO-2015102418-A2 | PEPTIDOMIMETIC COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATING ALLERGIC DISORDERS INCLUDING SAME | 이화여자대학교 산학협력단 | 2015-07-09 | — | — | WO | disclosed |
| US-9012838-B2 | Covalently functionalized nanodiamond-based MALDI matrices and methods of use thereof | UNIVERSITY OF SASKATCHEWAN (CA) | 2015-04-21 | — | — | US | disclosed |
| US-20140312218-A1 | COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2014-10-23 | — | — | US | disclosed |
| US-20140162245-A1 | NEW METHOD FOR ENZYME-MEDIATED SIGNAL AMPLIFICATION | DAKO DENMARK APS (DK) | 2014-06-12 | — | — | US | disclosed |
| US-8168372-B2 | semiconductors; microelectronic structures with nanosized features; acetylacetone complexes of titanium or zirconium; ethyl 2-cyano-3-(4-hydroxy-phenyl)-acrylate; crosslinker; solvent | BREWER SCIENCE INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20120070856-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2012-03-22 | — | — | US | disclosed |
| EP-2226314-A1 | Cross-linking agents | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- (FR) | 2010-09-08 | — | — | EP | disclosed |
| US-20080076064-A1 | METHOD OF CREATING PHOTOLITHOGRAPHIC STRUCTURES WITH DEVELOPER-TRIMMED HARD MASK | BREWER SCIENCE INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140312218-A1 | COVALENTLY FUNCTIONALIZED NANODIAMOND-BASED MALDI MATRICES AND METHODS OF USE THEREOF | ITGA2B, MMP2, ITGAV | ALDH1A1 1988/4885KDM4E 2997/4885CYP3A4 3354/4885 |
| US-20230210855-A1 | USE OF MCT1 INHIBITORS TO ENHANCE INSULIN SENSITIVITY | SLC2A1, SLC2A2, SLC16A1 | ALDH1A1 1679/4885KDM4E 1345/4885CYP3A4 2605/4885 |
| US-20120070856-A1 | CROSS-LINKING AGENTS | ORC3, TXN, PROC | ALDH1A1 2055/4885KDM4E 3357/4885CYP3A4 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.