Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014309 | 0.85 | TSHR (0.38) | TSHRTDP1CYP3A4MAPTCACNA1B | |
| SCHEMBL8629629 | 0.83 | TSHR (0.39) | TSHR | |
| SCHEMBL6272798 | 0.82 | TSHR (0.49) | TSHR | |
| SCHEMBL937816 | 0.80 | GLO1 (0.42) | TSHRMAPT | |
| SCHEMBL28663910 | 0.80 | — | — | |
| SCHEMBL28701636 | 0.80 | TSHR (0.56) | TSHRCYP3A4 | |
| SCHEMBL28968670 | 0.79 | THRB (0.49) | TSHRTDP1 | |
| SCHEMBL27725716 | 0.79 | TSHR (0.35) | TSHR | |
| SCHEMBL26980911 | 0.79 | ACHE (0.37) | TSHR | |
| SCHEMBL4564777 | 0.78 | LMNA (0.33) | TSHRTDP1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7422735-B1 | Use of crosslinked cationic polymers in skin cosmetic and dermatological preparations | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-09 | — | — | US | disclosed |