Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | DDO | Q99489 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015776 | 0.72 | DAO (0.40) | KMT2AOPRK1HTR1ASLC6A2ABCB11 | |
| SCHEMBL24804024 | 0.72 | CYP1A2 (0.47) | HTR1ASLC6A2ABCB11ADRA2APTGS1 | |
| SCHEMBL8015495 | 0.71 | CYP1A2 (0.34) | CYP1A2HSD17B10TSHR | |
| SCHEMBL24102936 | 0.71 | GAA (0.46) | HTR1ASLC6A2ABCB11ADRA2APTGS1 | |
| SCHEMBL8027733 | 0.70 | KDM4E (0.43) | KMT2ACYP1A2RXFP1LMNAMEN1 | |
| SCHEMBL25134416 | 0.69 | GAA (0.44) | KMT2AHTR1ASLC6A2ABCB11ADRA2A | |
| SCHEMBL8025613 | 0.68 | HPGD (0.44) | KMT2ALMNAMEN1ALDH1A1KDM4E | |
| SCHEMBL8039874 | 0.68 | — | — | |
| SCHEMBL8015412 | 0.68 | DHFR (0.37) | — | |
| SCHEMBL6755000 | 0.67 | GAA (0.42) | KMT2AHTR1ASLC6A2ABCB11ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | disclosed |