Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015495 | 0.85 | CYP1A2 (0.34) | HSD17B10TSHRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8015412 | 0.76 | DHFR (0.37) | — | |
| SCHEMBL8025613 | 0.73 | HPGD (0.44) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8914305 | 0.70 | KDM4E (0.56) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8015774 | 0.70 | KMT2A (0.39) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL19657006 | 0.66 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8038415 | 0.65 | ABL1 (0.31) | — | |
| SCHEMBL7774855 | 0.64 | KMT2A (0.38) | KDM4EMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL8038003 | 0.64 | ABL1 (0.30) | — | |
| SCHEMBL8039874 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | disclosed |