Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015412 | 0.85 | DHFR (0.37) | DHFR | |
| SCHEMBL8027733 | 0.85 | KDM4E (0.43) | CYP1A2CYP3A4CYP2C19HSD17B10TSHR | |
| SCHEMBL8025613 | 0.82 | HPGD (0.44) | HSD17B10 | |
| SCHEMBL16202643 | 0.73 | CASP1 (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19DHFR | |
| SCHEMBL8015774 | 0.71 | KMT2A (0.39) | CYP1A2HSD17B10TSHR | |
| SCHEMBL22434745 | 0.66 | NPEPPS (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19DHFR | |
| SCHEMBL8025972 | 0.66 | KDM4E (0.36) | HSD17B10TSHR | |
| SCHEMBL8038415 | 0.66 | ABL1 (0.31) | — | |
| SCHEMBL18000284 | 0.66 | MAPT (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19DHFR | |
| SCHEMBL13548554 | 0.65 | ALKBH5 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | disclosed |