Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015495 | 0.82 | CYP1A2 (0.34) | HSD17B10 | |
| SCHEMBL8015412 | 0.81 | DHFR (0.37) | — | |
| SCHEMBL8027733 | 0.73 | KDM4E (0.43) | HPGDKMT2AALDH1A1HSD17B10NPSR1 | |
| SCHEMBL8015774 | 0.68 | KMT2A (0.39) | HPGDKMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL12279026 | 0.66 | HPGD (0.61) | HPGDKMT2ASLC2A1ALDH1A1HSD17B10 | |
| SCHEMBL7210617 | 0.65 | PDE10A (0.43) | HPGDKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7118786 | 0.65 | PARP1 (0.43) | KMT2AALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5403210 | 0.64 | NR1H2 (0.48) | KMT2AALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL1429109 | 0.64 | HPGD (0.54) | HPGDKMT2ASLC2A1EGFRALDH1A1 | |
| SCHEMBL9386193 | 0.62 | HPGD (1.00) | HPGDKMT2AALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | disclosed |