Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 9/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12873251 | 0.91 | PPARG (0.44) | PPARGPPARDPPARAIGF1RAR | |
| SCHEMBL8009760 | 0.91 | PPARG (0.43) | PPARGPPARDPPARAIGF1RAR | |
| SCHEMBL8010593 | 0.89 | TAS2R8 (0.44) | PPARGPPARDPPARAIGF1RAR | |
| SCHEMBL8021401 | 0.89 | TAS2R8 (0.46) | IGF1RARTAS2R8 | |
| SCHEMBL8023307 | 0.89 | TAS2R8 (0.47) | IGF1RTAS2R8 | |
| SCHEMBL12873204 | 0.89 | AR (0.47) | PPARGPPARDPPARAIGF1RAR | |
| SCHEMBL12873241 | 0.89 | SLC6A2 (0.46) | PPARGPPARDPPARAIGF1RAR | |
| SCHEMBL8019464 | 0.87 | TAS2R8 (0.44) | IGF1RTAS2R8 | |
| SCHEMBL8023309 | 0.87 | TAS2R8 (0.46) | PPARGPPARDPPARAIGF1RTAS2R8 | |
| SCHEMBL12873224 | 0.86 | TAS2R8 (0.48) | IGF1RTAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046185-A1 | Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof | SANOFI-AVENTIS (FR) | 2011-02-24 | — | — | US | disclosed |
| US-20110046185-A1 | Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof | SANOFI-AVENTIS (FR) | 2011-02-24 | — | — | US | disclosed |
| WO-2009097998-A1 | ARYLCHALCOGENO-ARYLALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046185-A1 | Arylchalcogenoarylalkyl-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising these compounds and use thereof | PGC, LIPC, CEL | PPARG 7/4885PPARD 12/4885PPARA 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.