Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848569 | 0.81 | LMNA (0.47) | HIF1ALMNASLC6A2OPRM1ADRA1A | |
| SCHEMBL3675296 | 0.72 | LMNA (0.46) | HIF1ALMNASLC6A2OPRM1ADRA1A | |
| SCHEMBL3649813 | 0.68 | ESR1 (0.55) | HIF1ALMNASLC6A2OPRM1ADRA1A | |
| SCHEMBL12327370 | 0.66 | HIF1A (0.46) | HIF1ALMNASLC6A2OPRM1ADRA1A | |
| SCHEMBL2252628 | 0.66 | KDM4E (0.64) | HIF1ALMNAADRA1AADRB2CYP2D6 | |
| SCHEMBL1262889 | 0.66 | KDM4E (0.64) | HIF1ALMNAADRA1AADRB2CYP2D6 | |
| SCHEMBL723104 | 0.66 | KDM4E (0.64) | HIF1ALMNAADRA1AADRB2CYP2D6 | |
| SCHEMBL5076516 | 0.66 | KDM4E (0.64) | HIF1ALMNAADRA1AADRB2CYP2D6 | |
| SCHEMBL14465577 | 0.66 | KDM4E (0.64) | HIF1ALMNAADRA1AADRB2CYP2D6 | |
| SCHEMBL7740121 | 0.66 | PPARG (0.48) | HIF1ALMNASLC6A2OPRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6146429-A | DEVELOPER, COUPLER, BEESWAX AND PROTEIN HYDROLYZATES OR AMINO ACIDS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-11-14 | — | — | US | disclosed |