Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.51 |
| ▸ | TCF4 | P15884 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007630 | 0.97 | POLB (0.56) | POLBCA12CA9CA1CA2 | |
| SCHEMBL8013318 | 0.96 | POLB (0.55) | POLBCA12CA9CA1CA2 | |
| SCHEMBL8009400 | 0.87 | KMT2A (0.61) | KMT2AMEN1ALDH1A1MAPTPFKFB3 | |
| SCHEMBL7997927 | 0.82 | HTR6 (0.66) | CA9CA1CA2KMT2AALDH1A1 | |
| SCHEMBL8013124 | 0.79 | CA2 (0.61) | POLBCA12CA9CA1CA2 | |
| SCHEMBL3715141 | 0.78 | CA12 (0.75) | POLBCA12CA9CA1CA2 | |
| SCHEMBL664321 | 0.78 | KMT2A (0.75) | POLBCA12CA9CA1CA2 | |
| SCHEMBL22653513 | 0.78 | POLB (0.65) | POLBCA12CA9CA1CA2 | |
| SCHEMBL662338 | 0.78 | KMT2A (0.65) | POLBCA12CA9CA1CA2 | |
| SCHEMBL8018877 | 0.76 | POLB (0.62) | POLBCA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |