Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.66 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010004 | 0.87 | POLB (0.64) | HTR6CA1CA2KMT2ACYP19A1 | |
| SCHEMBL2242644 | 0.84 | HTR6 (0.72) | HTR6CA1CA2KMT2ACYP19A1 | |
| SCHEMBL8013124 | 0.82 | CA2 (0.61) | CA1CA2KMT2ACYP19A1ALDH1A1 | |
| SCHEMBL8018878 | 0.82 | POLB (0.59) | CA1CA2KMT2ACYP19A1ALDH1A1 | |
| SCHEMBL11438430 | 0.81 | HTR6 (0.62) | HTR6CA1CA2KMT2ACYP19A1 | |
| SCHEMBL8007630 | 0.80 | POLB (0.56) | CA1CA2KMT2AALDH1A1CA9 | |
| SCHEMBL28271812 | 0.80 | HTR6 (1.00) | HTR6CA1CA2KMT2ACYP19A1 | |
| SCHEMBL8013318 | 0.79 | POLB (0.55) | CA1CA2KMT2AALDH1A1CA9 | |
| SCHEMBL8010014 | 0.78 | PGR (0.65) | HTR6CA1CA2KMT2AALDH1A1 | |
| SCHEMBL24125035 | 0.76 | HTR6 (0.73) | HTR6CA1CA2KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |