Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010014 | 0.90 | PGR (0.65) | CA2LMNAMEN1KMT2ACA1 | |
| SCHEMBL2240850 | 0.85 | CYP19A1 (0.65) | CA2CA12CA9MAPTLMNA | |
| SCHEMBL7997927 | 0.82 | HTR6 (0.66) | CA2CA9LMNASMN1; SMN2KMT2A | |
| SCHEMBL7128721 | 0.82 | CA2 (0.58) | CA2CA12CA9MAPTLMNA | |
| SCHEMBL11444844 | 0.81 | CA2 (0.57) | CA2CA12CA9MAPTLMNA | |
| SCHEMBL8009551 | 0.81 | MEN1 (0.53) | CA2CA12CA9MAPTLMNA | |
| SCHEMBL8018878 | 0.79 | POLB (0.59) | CA2CA12CA9MAPTMEN1 | |
| SCHEMBL4948723 | 0.78 | HTR6 (0.72) | CA2CA12CA9MAPTLMNA | |
| SCHEMBL7808167 | 0.78 | CA2 (0.68) | CA2CA12CA9MAPTLMNA | |
| SCHEMBL21497057 | 0.78 | CA2 (0.68) | CA2CA12CA9MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |