Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021833 | 0.87 | ADORA3 (0.43) | RAD51CA1CA2ENPP2LMNA | |
| SCHEMBL7662908 | 0.85 | ENPP2 (0.53) | RAD51CA1CA2ENPP2LMNA | |
| SCHEMBL7668325 | 0.85 | ENPP2 (0.53) | RAD51CA1CA2ENPP2LMNA | |
| SCHEMBL8019501 | 0.82 | ADORA3 (0.56) | RAD51CA1CA2ENPP2LMNA | |
| SCHEMBL8019657 | 0.79 | ADORA3 (0.49) | CA1CA2LMNASMN1; SMN2ADORA3 | |
| SCHEMBL8008341 | 0.77 | MEN1 (0.45) | RAD51ENPP2LMNASMN1; SMN2ADORA3 | |
| SCHEMBL9359160 | 0.74 | ENPP2 (0.57) | CA1CA2ENPP2SMN1; SMN2HPGD | |
| SCHEMBL7656578 | 0.72 | ENPP2 (0.60) | RAD51CA1CA2ENPP2LMNA | |
| SCHEMBL7656554 | 0.72 | ENPP2 (0.60) | RAD51CA1CA2ENPP2LMNA | |
| SCHEMBL8008740 | 0.72 | ENPP2 (0.39) | RAD51CA1CA2ENPP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |