Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021833 | 0.88 | ADORA3 (0.43) | ADORA3ADORA2AADORA2BADORA1RORC | |
| SCHEMBL8008341 | 0.84 | MEN1 (0.45) | ADORA3ADORA2AADORA2BADORA1RAD51 | |
| SCHEMBL8008740 | 0.83 | ENPP2 (0.39) | ADORA3ADORA2AADORA2BADORA1RAD51 | |
| SCHEMBL8023363 | 0.82 | ADORA3 (0.56) | ADORA3ADORA2AADORA2BADORA1RORC | |
| SCHEMBL8019113 | 0.82 | RAD51 (0.40) | ADORA3ADORA2AADORA2BADORA1RORC | |
| SCHEMBL8021340 | 0.82 | VCAM1 (0.55) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL7665070 | 0.81 | RAD51 (0.59) | ADORA3ADORA2AADORA2BADORA1RORC | |
| SCHEMBL7678186 | 0.81 | ADORA3 (0.57) | ADORA3ADORA2AADORA2BADORA1RORC | |
| SCHEMBL7665009 | 0.81 | RAD51 (0.59) | ADORA3ADORA2AADORA2BADORA1RORC | |
| SCHEMBL9359160 | 0.78 | ENPP2 (0.57) | CA1CA2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |