Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019501 | 0.88 | ADORA3 (0.56) | ADORA3ADORA2AADORA2BADORA1RAD51 | |
| SCHEMBL8019113 | 0.87 | RAD51 (0.40) | ADORA3ADORA2AADORA2BADORA1RAD51 | |
| SCHEMBL8008341 | 0.82 | MEN1 (0.45) | ADORA3ADORA2AADORA2BADORA1RAD51 | |
| SCHEMBL7656578 | 0.82 | ENPP2 (0.60) | ADORA3ADORA2AADORA2BADORA1RAD51 | |
| SCHEMBL7656554 | 0.82 | ENPP2 (0.60) | ADORA3ADORA2AADORA2BADORA1RAD51 | |
| SCHEMBL9359160 | 0.79 | ENPP2 (0.57) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL8008740 | 0.77 | ENPP2 (0.39) | ADORA3ADORA2AADORA2BADORA1RAD51 | |
| SCHEMBL8021340 | 0.76 | VCAM1 (0.55) | MEN1KMT2AALDH1A1HTTLMNA | |
| SCHEMBL8021820 | 0.76 | CYP1A2 (0.60) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8018821 | 0.75 | MAPT (0.61) | MEN1KMT2AALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |