Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019501 | 0.83 | ADORA3 (0.56) | ENPP2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7667762 | 0.83 | ENPP2 (0.54) | ENPP2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7667811 | 0.83 | ENPP2 (0.54) | ENPP2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8021340 | 0.83 | VCAM1 (0.55) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8008341 | 0.81 | MEN1 (0.45) | ENPP2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8021833 | 0.77 | ADORA3 (0.43) | ENPP2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9359160 | 0.75 | ENPP2 (0.57) | ENPP2ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8018710 | 0.74 | LMNA (0.43) | ENPP2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10800759 | 0.73 | NPC1 (0.57) | ENPP2ALDH1A1CASP6CTDSP1MEN1 | |
| SCHEMBL11588532 | 0.72 | ENPP2 (0.44) | ENPP2LMNAALDH1A1CASP6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |