Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023083 | 0.89 | RAB9A (0.56) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA | |
| SCHEMBL8019190 | 0.89 | RAB9A (0.66) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA | |
| SCHEMBL7665164 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA | |
| SCHEMBL7665267 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA | |
| SCHEMBL8008535 | 0.88 | RAB9A (0.65) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA | |
| SCHEMBL7697941 | 0.83 | NPC1 (0.58) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA | |
| SCHEMBL7698195 | 0.80 | NPC1 (0.57) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA | |
| SCHEMBL7656637 | 0.78 | KMT2A (0.73) | ALDH1A1MAPK1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL8019200 | 0.78 | LMNA (0.55) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA | |
| SCHEMBL7666243 | 0.78 | L3MBTL1 (0.73) | ALDH1A1MAPK1SMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |