Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NSD2 | O96028 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021855 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MAPTTP53CYP3A4ALOX15 | |
| SCHEMBL9755397 | 0.71 | CDC25A (0.38) | ALDH1A1MAPTNPC1POLBRAB9A | |
| SCHEMBL224931 | 0.66 | GPR3 (0.41) | HTR2ACA1CA2ALDH1A1POLB | |
| SCHEMBL29711937 | 0.66 | GPR3 (0.41) | HTR2ACA1CA2ALDH1A1POLB | |
| SCHEMBL2354458 | 0.61 | S100A4 (0.41) | ALDH1A1MAPTEDNRBEDNRANPC1 | |
| SCHEMBL7754656 | 0.61 | MEN1 (0.38) | CA1CA2ALDH1A1MAPTEDNRA | |
| SCHEMBL194747 | 0.60 | HTR2A (0.38) | HTR2AALDH1A1MAPTHSD17B10TP53 | |
| Iodide SCHEMBL11463652 | 0.59 | MEN1 (0.36) | ALDH1A1MAPTEDNRAHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL11465934 | 0.59 | MEN1 (0.36) | ALDH1A1MAPTEDNRAHSD17B10TP53 | |
| SCHEMBL7680505 | 0.58 | HTR2A (0.34) | HTR2AHDAC4HDAC7HDAC5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000038673-A1 | COMPOSITIONS CONTAINING AND METHODS OF USING N-ACYL-1H-AMINOINDENES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2000-07-06 | — | — | WO | disclosed |