Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8615192 | 0.98 | CCR6 (0.35) | SIGMAR1CCR6TLR4MITFHSP90AA1 | |
| SCHEMBL8025758 | 0.77 | METAP1 (0.38) | METAP1 | |
| SCHEMBL8021901 | 0.76 | CTSL (0.33) | CCR6 | |
| Hydrochloric Acid SCHEMBL8616461 | 0.76 | METAP1 (0.39) | METAP1 | |
| SCHEMBL13899831 | 0.74 | — | — | |
| SCHEMBL5199186 | 0.74 | TLR4 (0.41) | CCR6TLR4MITFHSP90AA1METAP1 | |
| SCHEMBL6652483 | 0.73 | CCR6 (0.34) | CCR6MITFHSP90AA1METAP1 | |
| SCHEMBL6865388 | 0.73 | CA1 (0.45) | CCR6 | |
| SCHEMBL3146259 | 0.73 | CA1 (0.45) | CCR6 | |
| SCHEMBL8023959 | 0.73 | ALDH1A1 (0.42) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| EP-0780369-A1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | Grünenthal GmbH (DE) | 1997-06-25 | — | — | EP | disclosed |