SCHEMBL8020131

SCHEMBL8020131

Oc1cccc(SCl)c1SCl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.38
HPGD P15428 3/20 0.38
RECQL P46063 3/20 0.38
HSD17B10 Q99714 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
ALDH1A1 P00352 3/20 0.38
CA2 P00918 3/20 0.38
EGFR P00533 2/20 0.38
LMNA P02545 2/20 0.38
FYN P06241 2/20 0.38
MMP9 P14780 2/20 0.38
CA1 P00915 2/20 0.38
ADAMTS4 O75173 1/20 0.38
MMP2 P08253 1/20 0.38
MMP8 P22894 1/20 0.38
CA6 P23280 1/20 0.38
CDK2 P24941 1/20 0.38
MMP12 P39900 1/20 0.38
ADAMTS5 Q9UNA0 1/20 0.38
TSHR P16473 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9853388 0.85 ALDH1A1 (0.45) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL8531828 0.78 ALDH1A1 (0.33) ALOX15HPGDHSD17B10ALDH1A1CYP3A4
SCHEMBL7187789 0.77
Hydrogen Sulfide SCHEMBL10815992 0.75 ALDH1A1 (0.45) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL28338819 0.74 ALDH1A1 (0.36) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL5378592 0.74 CA2 (0.38) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL9985874 0.73
SCHEMBL7905205 0.70 ALDH1A1 (0.44) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL8888927 0.68 ALDH1A1 (0.50) ALOX15HPGDRECQLHSD17B10TDP1
SCHEMBL10833434 0.67 ALDH1A1 (0.32) HPGDTDP1ALDH1A1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3130635-B1 RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT SUMITOMO CHEMICAL CO (JP) 2020-02-26 EP disclosed
US-9909002-B2 Resin composition, cross-linked product, and method for manufacturing cross-linked product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-06 US disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-20170121516-A1 RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-04 US disclosed
US-9593194-B2 Method for producing olefin block polymer using group 4 transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-14 US disclosed
EP-3130635-A1 RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT Sumitomo Chemical Company Limited (JP) 2017-02-15 EP disclosed
US-20140275429-A1 METHOD FOR PRODUCING OLEFIN BLOCK POLYMER USING PLURALITY OF TYPES OF TRANSITION METAL CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-18 US disclosed
US-20140163173-A1 METHOD FOR PRODUCING OLEFIN BLOCK POLYMER USING GROUP 4 TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-06-12 US disclosed
US-8383848-B2 Transition metal compound and catalyst for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-26 US disclosed
US-20130041119-A1 OLEFIN POLYMER PRODUCING METHOD, ETHYLENE POLYMER, AND MOLD PRODUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-14 US disclosed
US-20110319578-A1 TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-29 US disclosed
EP-0968180-A1 SUBSTITUTED DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLOOXYGENASE II Nycomed Austria GmbH (AT) 2000-01-05 EP disclosed
WO-1998033769-A1 SUBSTITUTED DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLOOXYGENASE II NYCOMED AUSTRIA GMBH (AT) 1998-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319578-A1 TRANSITION METAL COMPOUND AND CATALYST FOR OLEFIN POLYMERIZATION AP1M1, SOD1, YAP1 ALOX15 121/4885HPGD 2366/4885RECQL 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.