Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020131 | 0.85 | ALOX15 (0.38) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL8888927 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL3917019 | 0.71 | ALOX15 (0.45) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL644137 | 0.71 | ALDH1A1 (0.45) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL8531828 | 0.70 | ALDH1A1 (0.33) | ALDH1A1ALOX15HPGDHSD17B10CYP3A4 | |
| SCHEMBL10887948 | 0.70 | TSHR (0.54) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL7187789 | 0.69 | — | — | |
| SCHEMBL3689566 | 0.67 | — | — | |
| SCHEMBL24448464 | 0.67 | TSHR (0.50) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL4128904 | 0.67 | CYP1A2 (0.45) | ALDH1A1TDP1LMNATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445926-A2 | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1991-09-11 | — | — | EP | disclosed |