Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443827 | 0.86 | IDO1 (0.50) | CNR1RARARARBRXRARXRB | |
| SCHEMBL12912969 | 0.81 | NPC1 (0.46) | IDO1LMNANPC1MAPTRAB9A | |
| SCHEMBL12912867 | 0.81 | IDO1 (0.50) | IDO1LMNANPC1MAPTRAB9A | |
| SCHEMBL8022326 | 0.80 | DRD2 (0.43) | CNR1RARARARBRXRARXRB | |
| SCHEMBL1366965 | 0.79 | RARA (0.64) | CNR1RARARARBRXRARXRB | |
| SCHEMBL7954347 | 0.78 | CNR1 (0.55) | CNR1RARARARBRXRARXRB | |
| SCHEMBL1366387 | 0.76 | HDAC1 (0.63) | CNR1RARARARBRXRARXRB | |
| SCHEMBL85731 | 0.75 | DRD2 (0.47) | DRD2TRPA1LMNACHRM2HTR1A | |
| SCHEMBL18088429 | 0.72 | HDAC3 (0.59) | RARARARBRXRARXRBRXRG | |
| SCHEMBL28428006 | 0.71 | ALDH1A1 (0.54) | IDO1LMNANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121415-A2 | IMPROVED PROCESS FOR PREPARING QUETIAPINE FUMARATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-10-09 | — | — | WO | disclosed |
| US-20080241949-A1 | Process for preparing quetiapine fumarate | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2008-10-02 | — | — | US | disclosed |
| US-20080241949-A1 | Process for preparing quetiapine fumarate | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241949-A1 | Process for preparing quetiapine fumarate | CYP3A5, CYP3A4, FH | CNR1 2336/4885RARA 3658/4885RARB 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.