Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022153 | 0.80 | CNR1 (0.46) | DRD2CNR1CNR2LMNACHRM2 | |
| SCHEMBL5443827 | 0.79 | IDO1 (0.50) | DRD2CNR1LMNACHRM2HTR1A | |
| SCHEMBL85731 | 0.78 | DRD2 (0.47) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL1132787 | 0.74 | USP2 (0.47) | DRD2CNR1CNR2PLECRARA | |
| SCHEMBL88348 | 0.71 | BACE1 (0.57) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL12844946 | 0.71 | DRD2 (0.47) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL8470 | 0.71 | DRD2 (0.47) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL12778506 | 0.71 | DRD2 (0.47) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL20829220 | 0.71 | DRD2 (0.47) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL10263717 | 0.70 | PLEC (0.65) | DRD2LMNAPLECNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121415-A2 | IMPROVED PROCESS FOR PREPARING QUETIAPINE FUMARATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-10-09 | — | — | WO | disclosed |
| US-20080241949-A1 | Process for preparing quetiapine fumarate | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2008-10-02 | — | — | US | disclosed |
| US-20080241949-A1 | Process for preparing quetiapine fumarate | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241949-A1 | Process for preparing quetiapine fumarate | CYP3A5, CYP3A4, FH | DRD2 465/4885CNR1 2336/4885CNR2 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.