Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024511 | 0.94 | TSHR (0.47) | FFAR1ALOX5NR4A2SMN1; SMN2 | |
| SCHEMBL8023084 | 0.92 | MRGPRX4 (0.49) | FFAR1NR4A2 | |
| SCHEMBL8023170 | 0.89 | FFAR1 (0.42) | FFAR1MMP12 | |
| SCHEMBL8020340 | 0.88 | MMP12 (0.48) | FFAR1ALOX5MAOBMMP12 | |
| SCHEMBL8024336 | 0.87 | FFAR1 (0.50) | FFAR1ALOX5MAOBMMP12 | |
| SCHEMBL8010235 | 0.84 | MMP12 (0.47) | FFAR1ALOX5MAOBMMP12 | |
| SCHEMBL8167144 | 0.84 | ACE (0.47) | — | |
| SCHEMBL8165378 | 0.84 | ACE (0.47) | — | |
| SCHEMBL8022292 | 0.84 | LPAR1 (0.42) | — | |
| SCHEMBL8026798 | 0.84 | ACE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156774-A | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-05 | — | — | US | claimed |
| US-6156774-A | Beta-thiopropionyl-amino acid derivatives and their use as beta-lactamase inhibitors | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-05 | — | — | US | disclosed |