Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397256 | 0.78 | CA1 (0.43) | MAPTTDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8024329 | 0.72 | MAPT (0.36) | MAPTTDP1L3MBTL1MAPK1NPSR1 | |
| SCHEMBL30128459 | 0.72 | KMT2A (0.53) | MAPTTDP1L3MBTL1MAPK1NPSR1 | |
| SCHEMBL128849 | 0.72 | KMT2A (0.53) | MAPTTDP1L3MBTL1MAPK1NPSR1 | |
| SCHEMBL3142212 | 0.70 | MAPT (0.58) | MAPTTDP1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL3142217 | 0.70 | MAPT (0.58) | MAPTTDP1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL17846838 | 0.69 | ALDH1A1 (0.40) | MAPTTDP1L3MBTL1MAPK1NPSR1 | |
| SCHEMBL19030004 | 0.69 | TDP1 (0.49) | MAPTTDP1L3MBTL1MAPK1NPSR1 | |
| SCHEMBL6129303 | 0.66 | NPC1 (0.58) | MAPTTDP1L3MBTL1MAPK1NPSR1 | |
| SCHEMBL18037665 | 0.66 | GPR35 (0.50) | MAPTTDP1L3MBTL1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000054103-A1 | CHIRAL POLYMER COMPOSITIONS EXHIBITING NONLINEAR OPTICAL PROPERTIES | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 2000-09-14 | — | — | WO | disclosed |