Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.46 |
| ▸ | HTR1A | P08908 | 9/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024959 | 0.78 | DRD1 (0.46) | DRD1BRD4 | |
| SCHEMBL1011227 | 0.78 | AURKA (0.39) | BRD4 | |
| SCHEMBL8027654 | 0.76 | DRD2 (0.46) | DRD2HTR1AHTR7DRD1HTR2A | |
| SCHEMBL8024853 | 0.74 | MEN1 (0.44) | DRD2HTR1AHTR7DRD1HTR2A | |
| SCHEMBL8028627 | 0.71 | DRD2 (0.55) | DRD2HTR1AHTR7DRD1HTR2A | |
| SCHEMBL8026602 | 0.71 | DRD2 (0.47) | DRD2HTR1AHTR7DRD1HTR2A | |
| SCHEMBL8025942 | 0.70 | HTR1A (0.46) | DRD2HTR1AHTR7DRD1HTR2A | |
| SCHEMBL8034433 | 0.70 | DRD2 (0.48) | DRD2HTR1AHTR7DRD1HTR2A | |
| SCHEMBL22049114 | 0.67 | ADRA1A (0.41) | BRD4 | |
| SCHEMBL20571881 | 0.67 | ADRA1A (0.41) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095253-A1 | 6-HALO-PYRAZOLO[1, 5-A]PYRIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR (MGLUR) MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-08-06 | — | — | WO | disclosed |