Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398701 | 0.91 | LMNA (0.73) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL1984377 | 0.90 | LMNA (0.71) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL9314768 | 0.86 | LMNA (0.67) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL19332232 | 0.81 | LMNA (0.61) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL7524136 | 0.81 | MAOB (0.64) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL19346040 | 0.80 | LMNA (0.60) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL19332234 | 0.80 | LMNA (0.60) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL3176303 | 0.80 | LMNA (0.63) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL8927983 | 0.79 | CYP2C19 (0.54) | MEN1KMT2AHTTMAPTGAA | |
| SCHEMBL8018553 | 0.79 | ALDH1A1 (0.56) | LMNAKMT2ARAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |