Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398701 | 0.89 | LMNA (0.73) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL1984377 | 0.87 | LMNA (0.71) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL9314768 | 0.83 | LMNA (0.67) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL1203178 | 0.82 | ALOX5 (0.67) | MAOBLMNAALDH1A1 | |
| SCHEMBL4759195 | 0.82 | MAOB (0.68) | MAOBMAPTMEN1TP53ALOX15 | |
| SCHEMBL7729899 | 0.81 | ALDH1A1 (0.58) | LMNAMAPTALDH1A1 | |
| SCHEMBL28621039 | 0.81 | CA12 (0.76) | MAOBLMNAMAPTMEN1TP53 | |
| SCHEMBL10335079 | 0.81 | GAA (0.68) | MAOBLMNAMAPTALDH1A1HTT | |
| SCHEMBL8024467 | 0.81 | LMNA (0.64) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL11685951 | 0.81 | MAPT (0.64) | LMNAMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839803-B1 | Substituted benzylurea derivatives and medicine containing the same | SS PHARMACEUTICAL CO (JP) | 2002-04-03 | — | — | EP | disclosed |
| CN-1061646-C | Substituted benzylurea derivatives and medicine containing the same | S S PHARMACEUTICAL CO LTD (JP) | 2001-02-07 | — | — | CN | disclosed |
| US-5922767-A | SELECTIVE INHIBITORS OF ACYLCOENZYME A:CHOLESTEROL ACYLTRANSFERASE (ACAT) IN MACROPHAGES; PROPHYLAXIS, TREATMENT OF ARTERIOSCLEROSIS | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| CN-1181377-A | Substituted benzylurea derivatives and medicine containing the same | S S PHARMACEUTICAL CO LTD (JP) | 1998-05-13 | — | — | CN | disclosed |
| EP-0839803-A1 | Substituted benzylurea derivatives and medicine containing the same | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-05-06 | — | — | EP | disclosed |