Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398701 | 0.94 | LMNA (0.73) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL1984377 | 0.92 | LMNA (0.71) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL28242786 | 0.87 | LMNA (0.52) | LMNAKMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL8024467 | 0.86 | LMNA (0.64) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL5034285 | 0.86 | CYP4Z1 (0.59) | LMNAHTTMAPTALDH1A1KDM4E | |
| SCHEMBL30643815 | 0.84 | CYP2C19 (0.64) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL76204 | 0.84 | CYP2C19 (0.64) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL19332232 | 0.83 | LMNA (0.61) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL7524136 | 0.83 | MAOB (0.64) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL19346040 | 0.82 | LMNA (0.60) | LMNAMEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |