Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025474 | 0.82 | TSHR (0.39) | HSP90AA1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8035585 | 0.81 | HSP90AA1 (0.41) | HSP90AA1KDM4EMAPTHPGDLMNA | |
| SCHEMBL8039002 | 0.81 | MAPT (0.39) | HSP90AA1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8035119 | 0.78 | KDM4E (0.40) | HSP90AA1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8039019 | 0.78 | HSP90AA1 (0.39) | HSP90AA1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8031650 | 0.77 | MEN1 (0.46) | MEN1KMT2ANPC1HPGDHTT | |
| SCHEMBL8039011 | 0.77 | HSP90AA1 (0.53) | HSP90AA1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL8039013 | 0.76 | ALDH1A1 (0.41) | HSP90AA1MEN1KMT2AHPGDLMNA | |
| SCHEMBL8032092 | 0.76 | ALDH1A1 (0.44) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL8039016 | 0.75 | HTT (0.42) | HSP90AA1KDM4ELMNAHTTCXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |