Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025473 | 0.82 | HSP90AA1 (0.37) | TSHRHPGDHSP90AA1MEN1KMT2A | |
| SCHEMBL8032092 | 0.79 | ALDH1A1 (0.44) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL8035585 | 0.79 | HSP90AA1 (0.41) | TSHRHPGDHSP90AA1KDM4EMAPT | |
| SCHEMBL8022338 | 0.78 | TRPM8 (0.46) | HPGDMEN1KMT2ANPC1 | |
| SCHEMBL8038341 | 0.78 | SMO (0.38) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL8035119 | 0.76 | KDM4E (0.40) | HPGDHSP90AA1MEN1KMT2AKDM4E | |
| SCHEMBL8039019 | 0.76 | HSP90AA1 (0.39) | TSHRHSP90AA1MEN1KMT2AKDM4E | |
| SCHEMBL8039011 | 0.75 | HSP90AA1 (0.53) | TSHRHPGDHSP90AA1MEN1KMT2A | |
| SCHEMBL8039013 | 0.74 | ALDH1A1 (0.41) | TSHRHPGDHSP90AA1MEN1KMT2A | |
| SCHEMBL8041629 | 0.74 | TDP1 (0.34) | TSHRHPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |