Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041234 | 0.88 | POLB (0.47) | ALDH1A1TRPV1MEN1KMT2AHSP90AA1 | |
| SCHEMBL8035102 | 0.81 | POLB (0.50) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL8034167 | 0.79 | APP (0.51) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8039002 | 0.78 | MAPT (0.39) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL8025473 | 0.76 | HSP90AA1 (0.37) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL8035119 | 0.76 | KDM4E (0.40) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL8041621 | 0.74 | MEN1 (0.40) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL8025474 | 0.74 | TSHR (0.39) | MEN1KMT2AHSD17B10HSP90AA1HPGD | |
| SCHEMBL8032092 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL8039016 | 0.72 | HTT (0.42) | ALDH1A1TRPV1GAAHSP90AA1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |