Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL8025597 | 1.00 | GRIK1 (0.39) | GRIK1GRIK2RAB9ANPC1PBRM1 | |
| Lysine SCHEMBL8025637 | 0.90 | GSR (0.40) | GRIK1GRIK2TDP1 | |
| Lysine SCHEMBL8025635 | 0.90 | GSR (0.40) | GRIK1GRIK2TDP1 | |
| Cyclohexylamine SCHEMBL7798411 | 0.88 | RAB9A (0.38) | RAB9ANPC1PBRM1TDP1MEN1 | |
| Cyclohexylamine SCHEMBL7798273 | 0.85 | KMT2A (0.47) | RAB9ANPC1PBRM1TDP1MEN1 | |
| Cyclohexylamine SCHEMBL8036007 | 0.82 | NPC1 (0.40) | GRIK1RAB9ANPC1EPHX1MEN1 | |
| Cyclohexylamine SCHEMBL8036004 | 0.82 | NPC1 (0.40) | GRIK1RAB9ANPC1EPHX1MEN1 | |
| Cyclohexylamine SCHEMBL8041276 | 0.79 | EPHX2 (0.33) | GRIK1GRIK2KIF11 | |
| Cyclohexylamine SCHEMBL8041254 | 0.79 | TP53 (0.41) | RAB9ANPC1MEN1KMT2AATM | |
| Cyclohexylamine SCHEMBL8041252 | 0.79 | TP53 (0.41) | RAB9ANPC1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |