Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210503 | 0.69 | KDM4E (0.37) | KDM4EALDH1A1NPSR1P2RX7MEN1 | |
| SCHEMBL7210500 | 0.69 | KDM4E (0.37) | KDM4EALDH1A1NPSR1P2RX7MEN1 | |
| Hydrochloric Acid SCHEMBL7210309 | 0.68 | KDM4E (0.39) | KDM4EALDH1A1NPSR1P2RX7MEN1 | |
| SCHEMBL8015495 | 0.66 | CYP1A2 (0.34) | HSD17B10TSHR | |
| SCHEMBL16202643 | 0.66 | CASP1 (0.39) | KDM4EHSD17B10MAPTTSHRHPGD | |
| SCHEMBL5347104 | 0.66 | KDM4E (0.54) | KDM4EALDH1A1HRH3 | |
| SCHEMBL18000121 | 0.61 | SLC6A4 (0.38) | KDM4EHSD17B10SYK | |
| SCHEMBL22434745 | 0.60 | NPEPPS (0.46) | KDM4EALDH1A1NPSR1HSD17B10MEN1 | |
| SCHEMBL18000284 | 0.60 | MAPT (0.46) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL13548554 | 0.59 | ALKBH5 (0.52) | KDM4EALDH1A1HSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061554-A1 | 1-AMINO ETHYLINDOLE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-10-19 | — | — | WO | disclosed |