2-Pyrrolidone

2-Pyrrolidone

SCHEMBL8026133

O=C1CCCN1.OC1=CC=COC1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.48
CRBN Q96SW2 2/20 0.42
FKBP5 Q13451 1/20 0.42
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL31581400 0.74
SCHEMBL16597354 0.74
2-Pyrrolidone SCHEMBL28375404 0.70
2-Pyrrolidone SCHEMBL3356160 0.70
2-Pyrrolidone SCHEMBL4655461 0.70 OR51E2 (0.88) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27610056 0.70
2-Pyrrolidone SCHEMBL4299593 0.70
2-Pyrrolidone SCHEMBL9304498 0.70 OR51E2 (1.00) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27827832 0.70
2-Pyrrolidone SCHEMBL2389 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6132474-A Fabric-cleaning bag having absorptive inner layer CUSTOM CLEANER, INC. (US) 2000-10-17 US disclosed
US-5997586-A Dry-cleaning bag with an interior surface containing a dry-cleaning composition REGENESIS, LLC 1999-12-07 US disclosed
US-5972041-A Fabric-cleaning kits using sprays, dipping solutions or sponges containing fabric-cleaning compositions CREATIVE PRODUCTS RESOURCE, INC. (US) 1999-10-26 US disclosed
US-5869410-A Fabric treatment and softener system for in-dryer use CREATIVE PRODUCTS RESOURCE, INC. (US) 1999-02-09 US disclosed
US-5746776-A Dry-cleaning kit for in-dryer use CREATIVE PRODUCTS RESOURCE, INC. (US) 1998-05-05 US disclosed
US-5658651-A Fabric treatment and softener system for in-dryer use CREATIVE PRODUCTS RESOURCE, INC. (US) 1997-08-19 US disclosed
US-5066413-A Fabric softening, antistatic agents, avoiding residues CREATIVE PRODUCTS RESOURCE ASSOCIATES, LTD. (US) 1991-11-19 US disclosed
US-5034222-A Solid having gelled phase and granular foam phases; substained release CREATIVE PRODUCTS RESOURCE ASSOCIATES, LTD. (US) 1991-07-23 US disclosed